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SM ISO690:2012 UNGUREAN, Andrei, GHELIS, Iulia, GHIMIȘLI, Iulia, CARAMAN, Eudochia, MIRON, Ion. Particularitățile de evoluție a meningitei tuberculoase la adulți. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 324. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Pag. 324-324 | ||||||
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Rezumat | ||||||
Background. Development of meningitis in patients with tuberculosis (TB) conditions a serious evolution of the disease, caused by irreversible changes that occur by cerebral edema. Objective of the study. Studying of evolution and assess treatment outcomes in adult patients with TB meningitis. Material and Methods. A cohort retrospective study was performed that included 46 adults with TB meningitis, undergoing treatment at the Municipal Clinical Hospital of Phthisiopneumology in Chisinau for the period 2000-2018 years. Results. Rate male/female - 4.75/1. Aged <40 years - 21 (46%). TB contact - 32 (70%) cases. The social risk factors was in 100%. Passive detection predominated - 44 (96%). Meningitis has been established in patients with pulmonary TB in 38 (83%) cases. The clinical forms of pulmonary TB were: infiltrative - 22 (68%), fibrocavitary - 6 (17%), disseminated - 4 (15%), 14 (30%) - extrapulmonary TB. Diagnosis was confirmed by distinctiv changes in the cerebrospinal fluid (CSF): serous CSF character, increased pleocytosis due to lymphocytes, positive Pandy reaction, hypoglycorahia. Treatment for sensitive TB - 31 (68%), for resistant TB - 15 (22%). The death of the patients - 41 (89%) cases. Conclusion. TB meningitis develops in young adults with contact TB. The TB meningitis diagnosis was confirmed by distinctiv typical changes in CSF. TB meningitis evolution is unfavorable. |
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Cuvinte-cheie Meningitis, tuberculosis, cephalo-rachidian liquid, meningită, tuberculoza, lichid cefalorahidian |
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