Articolul precedent |
Articolul urmator |
283 2 |
Ultima descărcare din IBN: 2024-03-20 22:45 |
SM ISO690:2012 CHIOSA, Diana. Biomarkerii inflamației – predictorii de risc cardiovascular la tineri. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 315. |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | |||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | |||||
|
|||||
Pag. 315-315 | |||||
|
|||||
Descarcă PDF | |||||
Rezumat | |||||
Background. The onset of the cardiovascular disease (CVD) anticipates the symptoms. In adulthood a number of inflammatory biomarkers are associated with the increased cardiovascular risk, however, these biomarkers are insufficiently studied in the young population. Objective of the study. Examine the high-sensibility C-reactive protein and IL-6 inflammatory biomarkers in young people. Material and Methods. A cross-cutting study was carried out on 88 young subjects, 23 (26.1%) men and 65 (73.9%) women, apparently healthy, mean age 19.3 ± 0.2 (17 to 25 age range). The concentration of the inflammatory biomarkers in blood was determined: the high-sensitivity C-reactive protein (hsCRP) by the enzyme-linked immunosorbent assay and IL-6 by the latex-immunoturbidimetry method. Results. The concentration of hsCRP ranged from 0.01 to 11.10 mg / l, averaging 0.56 ± 0.16 mg / l, with some sex differences: 0.61 ± 0, 14 mg / l in males versus 0.54 ± 0.21 (p <0.05) in females. The IL6 value ranged from 1.12 to 5.60 (2.23 ± 0.07) pg / ml, the results recorded in male subjects, statistically (2.34 ± 0.17 pg / ml) were significantly higher than in women (2.19 ± 0.07 pg / ml) (p <0.05). An increasing trend of IL-6 and hsCRP with age was registered, however, the differences between age groups ≤ 20 and> 20 years old were insignificant (p> 0.05). Conclusion. The inflammatory biomarkers have an increasing tendency in concentration with age, being more expressed among men. However, longitudinal studies are needed to assess the role of the studied biomarkers and their value in predicting the cardiovascular risk. |
|||||
Cuvinte-cheie biomarkers, cardiovascular disease, cardiovascular risk, biomarkeri, boala cardiovasculară, risc cardiovascular |
|||||
|