Articolul precedent |
Articolul urmator |
366 4 |
Ultima descărcare din IBN: 2021-11-04 03:58 |
SM ISO690:2012 TAMBALA, Diana, BOTNARU, Victor, MUNTEANU, Oxana. Sindroame paratimice la o pacientă tânără cu timom: bronșiectazii, eritroblastopenie, colită ulceroasă nespecifică . In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 303. |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | |||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | |||||
|
|||||
Pag. 303-303 | |||||
|
|||||
Descarcă PDF | |||||
Rezumat | |||||
Background. Thymomas are among the rare forms of mediastinal tumors, with more than 20 associated parathymic syndromes being described. The connection between autoimmune and thymoma manifestations has long been known, although the mechanisms involved are still a mystery. Objective of the study. Presenting parathymic syndromes in a young patient with thymoma and their evolution during 15 years of follow-up. Bronchiectasis can develop at any stage of the thymic neoplasm. Material and Methods. A case of a 41-year-old patient diagnosed with thymoma at the age of 30 is presented. Erythroblastopenia was confirmed by the reduction of erythrocyte series in bone marrow. Ulcerative colitis confirmed by histological examination. Thoracic HRCT (at age of 30-33-39-40 years) allowed pulmonary lesions assessment. Good’s syndrome was ruled out by normal serum immunoglobulins values. Results. The onset of the disease with low grade fever and retrosternal pain at age 27, misdiagnosed as pericarditis (mediastinal enlargement on chest X-ray) led to treatment with methylprednisolone. Pregnancy at 28 years old (birth of a healthy child) was the reason for the refusal of further examinations and surgical treatment, but contributed to the significant tumor growth with clinical manifestations of parathymic syndromes (erythroblastopenia with severe anaemia, ulcerative colitis), which did not disappear after thymectomy and splenectomy (over 2 years). Lung lesions have progressed from centrilobular nodules to bilateral extensive cystic bronchiectasis. Conclusion. The case illustrates rare forms of parathymic syndromes as well as the impact of thymectomy and splenectomy on their evolution. Thymoma-associated bronchiectasis predisposes to recurrent respiratory infections and progressive worsening of lung function, including in young patients. |
|||||
Cuvinte-cheie bronchiectasis, thymoma, erythroblastopenia, Colitis, Bronşiectazii, timom, eritroblastopenie, colită |
|||||
|