Articolul precedent |
Articolul urmator |
298 3 |
Ultima descărcare din IBN: 2023-07-03 19:41 |
SM ISO690:2012 GROPPA, Liliana, SÂRBU, Oxana. Diagnosticul precoce în spondiloartrita anchilozantă la femei. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 227. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | |||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | |||||
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Pag. 227-227 | |||||
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Background. In ankylosing spondylitis, it is difficult to start treatment early because of delayed diagnosis in men about 8.4 years, and in women 9.8 years from the onset of the disease. This is related to a number of subjective and objective factors. Objective of the study. Early diagnosis in ankylosing spondylitis in women. Material and Methods. In order to perform the study and satisfy the proposed objectives, 40 patients with the diagnosis established by AS, aged between 18-60 years, disease duration 7.2 ± 0.3 years were investigated. It was assessed for joint pain syndrome by analog visual scale, evaluation of inflammation indices: C-reactive protein, fibrinogen, ESR, HLA-B27, sacroiliac joint radiograph and HAQ index Results. At the VAS analysis, the joint pain syndrome is much stronger in women with HLA B27 positive. The average value of ESR in the group with HLA B27 positive was 28mm / h compared to 17 in those with HLA B27 negative, the values of C-reactive protein in the group with HLA B27 positive was 43 mg / dl, while those with HLA B 27 were negative 21 mg / dl. The BASFI index was prevalent in the HLA B27 positive group. HLA-B27 was present in 36 (90%) cases. Sacroileitis was present in 100% of cases, of which st Rg II in patients with HLA B27 negative compared to St Rg II-III in those with HLA B27 positive. HAQ index 15-40 in women with HLA B27 positive, compared to 12-30 in those with HLA B27 negative. Conclusion. For women with HLA B27 positive at the onset of the disease, it is characterized by a faster progression of sacroiliac joint damage, and a much more pronounced pain syndrome and a lower functional capacity compared to patients with HLA B27 negative. Highlighting the presence of HLA B-27 antigen. |
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Cuvinte-cheie ankylosing spondylitis, sacroiliac joints, HLA-B27, spondiloartrita anchilozantă, articulații sacroileace, HLA-B27 |
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