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Articolul urmator |
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Ultima descărcare din IBN: 2024-02-15 22:42 |
SM ISO690:2012 GOLUB, Aliona. Tratamentul paciențillor cu recăderi ale limfomului Hodgkin. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 225. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Pag. 225-225 | ||||||
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Rezumat | ||||||
Background. Hodgkin's lymphoma (LH) is a malignant tumor that develops in the lymphatic tissue. Although the treatment effectiveness and the healing potential are high, in some patients with local stages, there are up to 10-15% of relapses, which negatively influence the prognosis. Objective of the study. To study the results of relapse treatment in patients with stages I and II of HL. Material and Methods. The results of the treatment of relapses that developed in 78 patients, aged 18 to 78 years, with HL, initially diagnosed with stages I and II, with complete remissions due to the first-line therapy, were studied. The treatment was performed with 6-8 cycles of polychemotherapy (PChT): ABVD - in 33 patients, CVPP - in 38, BEACOPP - in 7 Results. The treatment efficacy was higher in patients in whom PChT BEACOPP was used; complete remission (CR) constituted 85.7%. In the cases of administration of PChT ABVD, CR accounted for 66.7%, and after PChT CVPP, CR was found only in 31.7% of cases. Progression-free survival (PFS) over 3 years was also higher in cases of PChT BEACOPP administration, and was constituted 100%, as opposed to PFS in the same terms, when applying PChT ABVD and CVPP, which amounted to 81.3 % and 73.7%, respectively. Conclusion. The BEACOPP regimen constituted the optimal treatment regimen for HL relapses. |
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Cuvinte-cheie Hodgkin's lymphoma, relapses, treatment, limfom Hodgkin, recăderi, Tratament |
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