Articolul precedent |
Articolul urmator |
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Ultima descărcare din IBN: 2024-03-18 21:34 |
SM ISO690:2012 IUNAC, Dmitrii, BALAN, Greta. Rezistenţa la antibiotice şi factorii de persistenţă a tulpinilor de Staphylococcus Aureus izolat din ulcere trofice. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 174. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | |||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | |||||||
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Pag. 174-174 | |||||||
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Background. The high antibiotic resistance of Staphylococcus aureus strains, together with the resistance to methicillin, the inducible resistance to clindamycin and the formation of biofilms present major problems in the therapy of infections caused by this species. Objective of the study. The aim of the study was to determine the antibiotic resistance and biofilm production capacity of Staphylococcus aureus strains isolated from trophic ulcers. Material and Methods. 138 S. aureus strains isolated from trophic ulcers were included in the study. Antibiotic susceptibility testing was performed by the diffusion method, and the ability to form biofilms by the quantitative adhesion test. Results. 93 (67.4%) S.aureus strains isolated from trophic ulcers were polyresistant to antibiotics, 69 (43.7%) were methicillin resistant, 31 (19.6%) were positive by D test and 81 ( 58.7%) produced biofilms. S. aureus strains were more sensitive to vancomycin (100%) and linezolid (90.6%). A higher rate of inducible clindamycin resistance was observed among methicillin-resistant strains (36.2%) compared to methicillin-sensitive S. aureus (6.7%). Similarly, higher rates of polyresistance and methicillin resistance were recorded among biofilm-producing strains compared to non-biofilm-producing strains (p <0.01). Conclusion. For a good management of S.aureus infections, it is important to include in the routine diagnosis the D test for the detection of inducible resistance to clindamycin, as well as the detection of biofilm production. |
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Cuvinte-cheie Staphylococcus aureus, antibioresistance, biofilms, trophic ulcers, Staphylococcus Aureus, antibiorezistenţă, biofilme, ulcere trofice |
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