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|Ultima descărcare din IBN:|
|Căutarea după subiecte |
similare conform CZU
|Neurologie. Neuropatologie. Sistem nervos (467)|
| SM ISO690:2012|
HADJIU, Svetlana; CĂLCÎI, Cornelia; FEGHIU, Ludmila; CUZNEȚ, Ludmila; LUPUŞOR, Nadejda; GRÎU, Corina; SĂRĂTEANU, Ina; GAVRILUŢĂ, Iulia; SPRINCEAN, Mariana; REVENCO, Ninel. Epilepsia structurală la copiii cu antecedente perinatale hipoxic-ischemice: variabile predictive. In: Buletin de Perinatologie. 2020, nr. 3(88), pp. 42-48. ISSN 1810-5289.
|Buletin de Perinatologie|
|Numărul 3(88) / 2020 / ISSN 1810-5289|
Introduction. The epilepsy (EP) is one of the leading condition in children who have had hypoxic-ischemic (HI) perinatal brain lesions (PBL). It can oft en be associated with mental retardation and oft en having an onset at an early age. Aim of the study is to determine the predictive variables in children with a history of HI PBL depending on the severity of the suff ering, to assess the risk of developing EP. Material and methods: Prospective study over a period of 2 years, on a group of 614 children, who had moderate (50.5%) and severe (49.5%) PBL. EP was diagnosed in 259 (42.2%) cases, the onset between 3 months and 2 years of age (peak 3-6 months), in children with moderate (27%) and severe (57.6%) PBL. We assessed some determinant variables for EP in the child aft er PBL based on a study protocol. Results. According to a logistic regression calculation, we determined the following variables with major risk in the development of EP in the child aft er PBL: (1) intrauterine hypoxia (p <0.001), (2) severe PBL at birth (p <0.006), (3 ) disorders of consciousness (p <0.003), (4) the presence of neonatal convulsions (p <0.004), (5) the pathological electroencephalographic pathway in the fi rst two weeks aft er birth (p <0.000). The probability of developing EP in the child who suff ered from PBL in the case of the combination of the 5 variables is high (RP + = 99.7%). Conclusions. The EP can develop at any age, especially in the child with severe PBL, the most vulnerable being the infant age. The association and number of predictive variables determine various individualized results.
epilepsy, perinatal brain lesions, variable,
эпилепсия, перинатальные поражения мозга, факторы