Introduction. Liver disease can cause significant morbidity in both pregnant women and their infants. We discuss clinical conditions that are seen only in pregnant women and affect the liver: from Intrahepatic Cholestasis of Pregnancy (0.5% - 1.5% prevalence), to the more frequent condition of preeclampsia (10% prevalence) and its severe form; haemolysis, elevated liver enzymes, and a low platelet count syndrome (12% of pregnancies with preeclampsia) - HELLP syndrome. The pathogenesis is not completely known, there are theories. Anyway all of them suggest the changes in the maternal body due to the change of pregnancy hormones. These conditions affect not only the mother but also the baby. It is important to make an early diagnosis and prevent the outcomes with simple medication. Aim of study. The study of clinical and paraclinical features in women with different types of hepatic pathology in the third trimester of pregnancy. Material and methods. The study is retrospective, based on the results of the medical records; year 2016-2017; Therapy Department, Obstetrical Emergency Department, Intensive Care Department; Public Health Institution, Mother and Child Institution. The study group consists of 43 pregnant patients: 12 patients with preeclampsia, 12 patients with HELLP syndrome, 19 patients with intrahepatic cholestasis of pregnancy. The control group consist of 10 patients with gestational hypertension. Results. Basic clinical symptoms were found: headache, edema, visual disorders, epigastric pain, HTA characteristic for preeclampsia and HELLP syndrome; pruritus characteristic for intrahepatic cholestasis of pregnancy. A significant statistical difference was observed between urinary protein and lactate dehydrogenase (r=0.64; p<0.05) in HELLP syndrome. Pruritus disappeared in 50% cases and diminished substantially in 50% cases of intrahepatic cholestasis of pregnancy postpartum. Conclusions. The clinical picture of females in their third trimester of pregnancy, with different types of hepatic lesions denotes a notorious polymorphism.