Alterations of brain structure linked to myoclonic epilepsy
Închide
Articolul precedent
Articolul urmator
472 0
SM ISO690:2012
VATAMAN, Anatolie. Alterations of brain structure linked to myoclonic epilepsy. In: IFMBE Proceedings: . 4th International Conference on Nanotechnologies and Biomedical Engineering, Ed. 4, 18-21 septembrie 2019, Chişinău. Switzerland: Springer Nature Switzerland AG, 2020, Ediția 4, Vol.77, pp. 535-539. ISBN 978-303031865-9. ISSN 16800737. DOI: https://doi.org/10.1007/978-3-030-31866-6_96
EXPORT metadate:
Google Scholar
Crossref
CERIF

DataCite
Dublin Core
IFMBE Proceedings
Ediția 4, Vol.77, 2020
Conferința "Conference on Nanotechnologies and Biomedical Engineering"
4, Chişinău, Moldova, 18-21 septembrie 2019

Alterations of brain structure linked to myoclonic epilepsy

DOI: https://doi.org/10.1007/978-3-030-31866-6_96

Pag. 535-539

Vataman Anatolie12
 
1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
2 Emergency Institute of Medicine
 
Proiecte:
 
Disponibil în IBN: 26 octombrie 2020


Rezumat

Recent neuroimaging studies suggest that frontal lobe and thalamus are the key structures involved in generation of myoclonic seizures. However, data indicating clear structural alterations of other grey matter (GM) regions in this seizure type is limited. Thus, our purpose was to characterize the cortical and subcortical volumes in patients with myoclonic seizures. We quantified brain structural measures (cortical and subcortical GM volumes) extracted from 3T magnetic resonance images (MRI) across 40 patients (mean age ± standard deviation: 25 ± 7 years; 14 males) with myoclonic seizures and 40 healthy subjects (23 ± 5 years; 14 males). A statistically significant difference in cortical volumes between patients and healthy subjects was found in the following clusters: left superior parietal, postcentral and fusiform; right middle temporal and bilateral precentral, superior frontal and precuneus areas (all p < 0.05). Analysis of subcortical volumes revealed significantly smaller volumes of bilateral thalamus and caudate in patients compared to healthy. These findings support the hypothesis of aberrant cortico-thalamic networks in patients with myoclonic seizures and extend these to basal ganglia. 

Cuvinte-cheie
magnetic resonance imaging, Myoclonic epilepsy, Volumetry