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1033 3 |
Ultima descărcare din IBN: 2023-05-21 19:37 |
SM ISO690:2012 BOUR, Alin, TARGON, Roman, VATAMAN, Vladimir. Testarea experimentală in vivo a biocompatibilităţii plaselor chirurgicale, utilizate în chirurgia reconstructivă a peretelui abdominal. In: Curierul Medical, 2012, nr. 1(325), pp. 16-21. ISSN 1875-0666. |
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Curierul Medical | ||||||
Numărul 1(325) / 2012 / ISSN 1875-0666 | ||||||
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Pag. 16-21 | ||||||
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The purpose of this study was to compare biological tissue response to three types of surgical mesh. In the present study a low-weight macroporous polypropylene mesh (PPLW) was compared to heavy-weight microporous polypropylene mesh (PPHW) and polyethylene terephthalate (PET) mesh. All three types of surgical non-absorbable mesh with different pore size were implanted in an preperitoneal position in the abdominal wall of 60 rats. Five animals per group were sequentially sacrificed at 7, 14, 30 and 90 days after implantation. The mesh samples were investigated by light microscopy. The morphometric parameters of the mesh area and surrounding host tissue were examined in regard to the inflammatory infiltrate, the number of granulocytes, macrofages, giant cells, fibroblasts, collagen deposition and neo-angiogenesis. Conclusions: the experimental data confirmed the development of the chronic inflammatory foreign body reaction at the interface to all three types of implanted meshes. Polypropylene meshes tended to induce higher acute inflammatory reaction and connective tissue formation, while polyethylene terephthalate mesh tended to induce the giant cell type of foreign body reaction. The experimental data confirmed an improved biocompatibility and superior integration in recipient tissue for the „low weight” polypropylene mesh with large pores.
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Cuvinte-cheie polypropylene mesh, polyethylene terephthalate mesh, foreign body reaction, tension-free hernia repair |
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