Viabilitatea microorganismelor după liofilizare depinde de mai mulţi factor, unul dintre care este mediul de protecţie. În acest studiu în calitate de lioprotectanţi, la liofilizarea tulpinilor Penicillium sp. 11 şi Streptomyces sp. 205, au fost utilizate nanoparticulele (NP) de fier (Fe3O4, Fe(0)) şi substanţele de origine cianobacteriană: extractul etanolic 50% şi polizaharidele sulfatate (PSS). S- a demonstrat că, NP de fier  pot diminua sau menţine viabilitatea tulpinilor la nivelul martorului, iar substanţele de origine cianobacteriană pot acţiona inhibitor (Penicillium sp. 11) sau stimulator (sporeşte viabilitatea tulpinii Streptomyces sp 205 cu 17-19% faţă de martor).

The viability of microorganisms after lyophilization depends on several factors, one of which is the protective medium. In this study as lyoprotectants for lyophilization of Penicillium sp. 11 and Streptomyces sp. 205, served: the iron nanoparticles (NPs) – (Fe3O4, Fe (0)) and the substances of cyanobacterial origin, 50% ethanolic extract and sulphated polysaccharides (PSS). It has been shown that iron NPs can diminish or maintain the viability of strains at level of control sample, and substances of cyanobacterial origin can act as inhibitors (Penicillium sp. 11) or stimulants (increases the viability of the Streptomyces sp. 205 strain by 17-19% in comparison with control).