Soils from the dyked precincts Sireasa and Pardina of the Danube Delta were analyzed, belonging to the Calcaric Fluvisol, Calcaric Gleyosol, Mollic Calcaric Gleyosol, Mollic Fluvisol, Calcaro-Calcic Kastanozem, and Calcaro-Calcic Chernozem7 types. The soils are slightly alkaline, with a moderate carbonates content, low up to average humus and total nitrogen ones, and diverse, from very low to very high, of mobile phosphorus and potassium. Some of them have a salinization level up to 688 mg soluble salts per 100 g soil. The mobile and total selenium contents are high, superior to the average general content of the World’s soils and to the contents of the South-Eastern Romanian Plain and Central and South Dobrogea soils. In fact, they are the highest values registered so far in Romania’s soils. In general, the soils within the built-up area have higher values than those of the outside built-over one both for selenium and other chemical elements. Direct proportionality relations were established between the total selenium content and some of the agrochemical soil properties (indirect with the pH), all of them statistically ensured, and also between the total and mobile selenium contents, on one hand, and the micro elements (heavy metals) contents on the other hand. The ensuring degree of the selenium’s correlations with some heavy metals increases by depth which shows the geogenic origin of the chemical elements in the Delta soils. Although the Danube Delta is a deprived area the selenium content of the analyzed soils is high without reaching, though, toxicity levels.