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SM ISO690:2012 RUSSU, Eugen, GROPPA, Liliana, BABIUC, Constantin, GONŢA, Liudmila. Conexiunile dintre tabloul clinic al artritei psoriazice şi clasele HLA la pacienţii din Republica Moldova.. In: Sănătate Publică, Economie şi Management în Medicină , 2011, nr. 2(2), p. 47. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | |||||
Numărul 2(2) / 2011 / ISSN 1729-8687 /ISSNe 2587-3873 | |||||
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Pag. 47-47 | |||||
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The aim of this study was to analyze clinical manifestations of psoriatic arthritis and associations with human leukocyte antigens (HLA-antigens) and identifying markers for aggressive joint disease. The prevalence of inflammatory joint manifestations, such as poliarthritis, axial disease and mutilate arthritis was high among patients with psoriatic arthritis in Republic of Moldova. There were several strong association between HLA-antigens (B7, B17, B27, B37, A2, A3, A7, A29) and psoriatic arthritis. The strongest predictive factors among patients with poliarthritis and axial disease of psoriatic arthritis for an aggressive disease were HLA-A3, A29, B27, B37 with a significant linkage (p = 0.0001, RRf = 2.9). |
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