Nitrogen heterocycles are invaluable compounds demonstrating fascinating potential applications for medicine, opto-electronics, agriculture, etc., being a top and widely discussed research field in modern science. Over the past decades advances in supamolecular chemistry have lead to the development of miniaturized devices based on assemblies of single molecules that can execute functions on a “molecular level”. Two of the most promising devices, widely discussed nowadays, are the fluorescent chemosensors and logic gates (or systems), somehow closely related. Within this work we present some core results obtained by our group in the field of polifunctional nitrogen derivatives as smart versatile building blocks for multiple tasks: drugs, fluorescent chemosensors, logic gates, etc.