In Republic of Moldova Lymantria dispar L. provokes massive defoliation in forests of oaks and other forest species, and in fruit orchards. The use of pesticides to combat, provokes serious problems for environment, but and human health. As an alternative method to combat, was proposed using baculoviral preparations, that ensuring a high level of effectiveness, showing properties of specificity. In many countries with advanced forestry services also applied to surfaces prepared imposing. In the Republic of Moldova were carried out investigation on highlight biological agents and demonstrate the use of preparations baculovirale, but level the application of these means now remains reduced, recording various problems, who awaiting approach and resolve [1, 9, 12].