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Ultima descărcare din IBN: 2020-05-18 07:50 |
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617.379-008.64:617-002.44-06-089.843 (1) |
Științe medicale. Medicină (11136) |
SM ISO690:2012 PETRUSHENKO, V., GREBENIUK, D., APASOVA, N.. Biological stimulation of diabetic ulcers healing . In: Arta Medica , 2019, nr. 3(72), p. 159. ISSN 1810-1852. |
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Arta Medica | ||||||
Numărul 3(72) / 2019 / ISSN 1810-1852 /ISSNe 1810-1879 | ||||||
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CZU: 617.379-008.64:617-002.44-06-089.843 | ||||||
Pag. 159-159 | ||||||
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Introduction: Despite many studies, diabetes does not respond to radical treatment, and footulcers do not heal for a long time. Aim: The aim of our study was toevaluatethe reparatory efect of platelet-rich plasma (PRP) in the treatment of patients with diabetic foot in stage 2. Materials and methods: The study included 32 patients with diagnosis of diabetic foot in stage 2. At the time of inclusion in the study, all patients had a defect of the skin and subcutaneous fat on the foot, measuring 3-6 cm2, which was not corrected by traditional methods for 3-4 months. All patients were divided in 2 groups: comparison group (n=18 (56.25%) – standard therapy; study group (n=14;43.75%) – standard therapy and local serial administration of PRP. The area of the ulcers was measured before manipulation, as well as at 1 week intervals until the ulcer was completely healed. Results: Our experience with PRP in the treatment of patients with diabetic foot in stage 2 demonstrated the efectiveness of this technique. A progressive, signiicant (p<0.01) decrease in the area of the ulcerative defect starting from the 14th day was noted. When using PRP, we managed to achieve complete healing of diabetic ulcers in 64.2% of patients on day 35 and in 100% of patients on day 42. Conclusion: Local administration of an PRP allows the complete healing of diabetic ulcers in stage 2 with an area of 3-6 cm2 for 6 weeks. |
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Cuvinte-cheie diabetic ulcer, platelet-rich plasma, reparation. |
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