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547.441:615.9:582.273 (1) |
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Toxicologie generală. Studii generale asupra otrăvurilor şi otrăvirii (intoxicaţiei) (45) |
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SM ISO690:2012 CEPOI, Liliana, RUDI, Ludmila, CHIRIAC, Tatiana, MISCU, Vera, RUDIC, Valeriu. Dialdehida malonică – un potențial marcher al toxicității nanoparticulelor în mediul acvatic. In: One Health and Risk Management, 2020, nr. 1(1), pp. 64-71. ISSN 2587-3458. DOI: https://doi.org/10.5281/zenodo.3701197 |
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One Health and Risk Management | ||||||
Numărul 1(1) / 2020 / ISSN 2587-3458 /ISSNe 2587-3466 | ||||||
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DOI:https://doi.org/10.5281/zenodo.3701197 | ||||||
CZU: 547.441:615.9:582.273 | ||||||
Pag. 64-71 | ||||||
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Introduction. As a result of increased production and spread in the environment, nanoparticles can pose a significant risk to public health. To date, the toxicity data of nanoparticles collected, using traditional models and methods, are contradictory and inconsistent. Highlighting the significant methods and markers of nanoparticle toxicity is a current research direction. Material and methods. The strain of red microalgae Porphyridium cruentum CNMAR01, known as a lipid manufacturer, was used as object of study. The toxic effect of CdSe (3-7 nm), ZnSe (40 nm) and ZnS (30-35 nm) nanoparticles was tested. The amount of malondialdehyde was determined based on thiobarbituric acid reactive substances. Results. A close correlation between the amount of biomass and malondialdehyde in the cells of red microalgae Porphyridium cruentum has been established for nanoparticle concentration ranges which have a toxic effect on Porphyridium cruentum. Conclusions. Malondialdehyde can be considered as a marker of nanoparticle toxicity. |
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Cuvinte-cheie nanoparticles, toxicity tests, malondialdehyde, Porphyridium cruentum, nanoparticule, teste de toxicitate, dialdehida malonică, Porphyridium cruentum |
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