POPs polluted site at pesticide storages is an important issue for Republic of Moldova. The aim of this study is a review of Environmental Risk Assessment (ERA) methodologies on regional (ranking system) and local level (conceptual model) for individual sites. Three principal factors were taken into consideration: level and pollution spectrum, risk receptors,and distribution potential. The pollution spectrum was complex and consists of five groups of POPs and other toxic substances (trifluraline, triazines, PAHs, heavy metals). Risk receptors include two factors: distance of risk receptors to polluted site; importance and vulnerability of every receptor. Risk index for distribution potential included particularities of site for the distribution of toxic substances to the environment and several ways of dispersing pollution in the environment: wind dispersion; infiltration to groundwater; surface runoff; and anthropogenic factor. The calculation of risk value on the regional level included balance between all factors using GIS approach. Several sites with different conditions were investigated for ERA procedure in Lower Danube Area. ERA on local level included a formulation of “conceptual model” of the pollution fate to risk receptors. This procedure has following key steps: 1 – hazard identification; 2 – consequences identification in the case when the hazard occurred; 3 estimating the magnitude of the consequences (spatial and temporary); 4 estimation of the consequence probability or the exposure assessment; 5 – the evaluation of risk importance (risk characteristic or assessment). The risk management is proposed for the realization by several modes: the reduction or modification of pollution sources; managing or elimination of migration pathways; receptor modification. The polluted site remediation project should to be developed individually to take into consideration a polluted area, volume of contaminated soil, geological conditions, and pollution spectrum. Acknowledgement: We acknowledge the funding from ENPI project code MIS ETC 1676 - INPOLDE (2013-2015) and ENI project eMS code BSB27 - MONITOX (2018-2021).