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616.831-002-092:612.017.1]-036.1 (1) |
Neurology. Neuropathology. Nervous system (963) |
Physiology. Human and comparative physiology (719) |
SM ISO690:2012 HADJIU, Svetlana, NEAMŢU, Mihai-Bogdan, CĂLCÎI, Cornelia, CAZAN, Corina, SPRINCEAN, Mariana, REVENCO, Ninel. Encefalita imună: considerații în baza unui caz clinic. In: Buletin de Perinatologie, 2019, nr. 2(83), pp. 94-101. ISSN 1810-5289. |
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Buletin de Perinatologie | |||||
Numărul 2(83) / 2019 / ISSN 1810-5289 | |||||
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CZU: 616.831-002-092:612.017.1]-036.1 | |||||
Pag. 94-101 | |||||
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Immune encephalopathies can be triggered by an infection or a tumor. Th ere is an abnormal immune response. In recent years, new antibodies have been discovered which mediate autoimmune encephalitis. In addition to classical onconeuron antibodies, which are directed against intracellular neuronal agents recently, a novel group of antibodies to neuronal cell-surface and synaptic antigens associated with diff erent CNS-syndromes, has been discovered. The spectrum of autoimmune disorders of the central nervous system in immune encephalopathies is wide, and increased further with the discovery of disorders associated with antibodies directed against the neuronal membrane surface. Many of these conditions present signs of dysfunction of the limbic system, and may occur as a consequence of some infections, although a large part of the cases have a paraneoplastic character. Th ey may occur with milder symptoms, and present no abnormalities in the exams usually used in the investigation of paraneoplastic encephalitis. Cases in children may be misdiagnosed as psychological or other types of neurological disorders. Th e syndromes in this group can be successfully treated with immunotherapy. Th e present study describes a clinical case of a child with immune encephalopathies. |
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Cuvinte-cheie immune encephalopathies, autoantibodies, clinical syndromes, neurological disorders, immunotherapy, аутоиммунный энцефалит, аутоантитела, клинические синдромы, неврологические нарушения, иммунотерапия |
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