Antimicrobial activity of extracts from forestry wastes
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LUPAŞCU, Lucian, TIMBALIUC, Nina, PETROV, Natalia, LUPASCU, Tudor. Antimicrobial activity of extracts from forestry wastes. In: Ecological and environmental chemistry : - 2017, Ed. 6, 2-3 martie 2017, Chișinău. Chisinau, Republic of Moldova: Academy of Sciences of Moldova, 2017, Ediția 6, pp. 55-56.
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Ecological and environmental chemistry
Ediția 6, 2017
Conferința "Ecological and environmental chemistry 2017"
6, Chișinău, Moldova, 2-3 martie 2017

Antimicrobial activity of extracts from forestry wastes


Pag. 55-56

Lupaşcu Lucian, Timbaliuc Nina, Petrov Natalia, Lupascu Tudor
 
Institute of Chemistry of the Academy of Sciences of Moldova
 
 
Disponibil în IBN: 6 martie 2019


Rezumat

In recent time, many chemists focus their research for obtaining of the biological active substances from natural raw material, which can be used in an intact or chemically modified form in different areas of human activities. The plants constitute true biochemical manufactories, which synthesize both basic substances necessary for their survival and a wide range of compounds as well, that can be extracted and used in medicine, food industry, perfumery, textile industry etc. So, the research in the field of bioactive extracted compounds from different vegetal raw material is certainly actual and of a high significance [1-2]. A valuable raw material for obtaining this category of substances can be the sawdust from the wood processing factories. The newly compound was obtained as a result of extraction of bioactive substances in an ultrasonic field during 30 minutes at the temperature of 25 Celsius degrees and the weight ratio of “vegetal product-solvent” 1:5 using as a solvent the ethyl alcohol of 50%. This newly obtained extracts has a low water solubility, which reduces essentially its using potential. As a result of oxidation, the extract obtained from forestry wastes is solubilized, this process being accompanied with the formation of new organic compounds, containing carboxylic, peroxidic, alcoholic and phenolic functional groups. The total contain of the acid functional groups (carboxylic and phenolic) as well the antioxidant activity of the modified compound have been determined. The obtained compound was tested regarding its antimicrobial activity. As test-cultures were used bacterial strains from Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus species and a fungal strain of Candida albicans. The minimal bactericidal concentration varied in the range of 0,25-0,5%, the antifungal activity was at the level of 1%.These values of antimicrobial activity are similar those presented by Enoxil. The advantage of the newly obtained compound consist in that is more accesible regarding the availability of the raw material and its more cheaper in obtaining in comparison with the Enoxil compound. The analysis of the obtained results allows to conclude that the newly modified compound shows interest for future microbiological and pharmacological research, due to its high antioxidant activity, approximately AA=85% (DPPH test) and AA=55% (ABTS test) for the 1% water solution, and a considerable amount of acid functional groups (Ctotal/g=4,382).