The correlation between lipid peroxidation processes, antioxidant system and Helicobacter pylori infection in patients with various forms of evolution of duodenal ulcer The results of comparative analysis of clinical clues to explore complex paraclinic registered 104 patients with duodenal ulcer were conventionally defined two clinical groups: the benign variant and severe duodenal ulcer. Regardless of the presence or absence of H. pylori infection in both groups of patients were confirmed increased activity of lipid peroxidation system and decreased activity of antioxidant system compared with controls and these changes were significantly more pronounced in patients with H. pylori associated duodenal ulcer.

În rezultatul analizei comparative a indiciilor clinico-paraclinici înregistraţi la explorarea complexă a 104 bolnavi cu ulcer duodenal s-au definit convenţional două grupuri clinice: cu variantă de evoluţie benignă şi severă de ulcer duodenal. Indiferent de prezenţa sau lipsa infecţiei H.pylori, în ambele grupuri de pacienţi s-au atestat creşterea activităţii sistemului de peroxidare lipidică şi scăderea activităţii sistemului antioxidant comparativ cu lotul martor şi aceste modificări au fost semnificativ mai pronunţate la pacienţii cu UD H.pylori asociat.