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SM ISO690:2012 SOROCEANU, Ala. Sindroame neuropsihiatrice în lupusul eritematos sistemic: evaluarea lor prin utilizarea instrumentelor neuropsihologice
validate
. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2010, nr. 3(11), pp. 76-83. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 3(11) / 2010 / ISSN 1857-1719 | ||||||
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Pag. 76-83 | ||||||
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Diagnosis problems in neuropsychiatric SLE remains a challenge for clinicians. Our purpose was to study the neuropsychiatric syndromes in patients with systemic lupus erythematosus and their impact on quality of life. We examined 60 patients who met the ACR
diagnostic criteria, Hochberg M. 1997. Special investigations focused assessment of disease
activity, index of organic damage, cumulative glucocorticosteroid dose administered, assessing quality of life according to SF-36 questionnaire. Activity of disease in SLE patients showed that in patient with the nervous system involvement was medium/high in 81. 2%, while in group without nervous system involvement - medium/low in 85.7% cases. Analyzing the data of index of organic damage (DI) got low level in both groups found it, when high and very high found only in patients with nervous system affecting. Clinical correlations between DI and nervous system involvement in systemic lupus was found. Application of SF-36 questionnaire in patients with systemic lupus erythematosus showed that low quality of life is determined by the involvement of the nervous system, predominantly by mental health. |
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