Clinical efficacy of midline lumbar interbody fusion arthrodesis with neuronavigation-guided cortical bone trajectory screws in the treatment of degenerative lumbar spondylolisthesis:a prospective randomized controlled trial
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Pathology of the organs of locomotion. Skeletal and locomotor systems (462)
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BORODIN, Serghei. Clinical efficacy of midline lumbar interbody fusion arthrodesis with neuronavigation-guided cortical bone trajectory screws in the treatment of degenerative lumbar spondylolisthesis:a prospective randomized controlled trial. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2023, vol. 10, nr. 1, pp. 9-15. ISSN 2345-1467. DOI: https://doi.org/10.52645/MJHS.2023.1.02
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Revista de Ştiinţe ale Sănătăţii din Moldova
Volumul 10, Numărul 1 / 2023 / ISSN 2345-1467

Clinical efficacy of midline lumbar interbody fusion arthrodesis with neuronavigation-guided cortical bone trajectory screws in the treatment of degenerative lumbar spondylolisthesis:a prospective randomized controlled trial

DOI: https://doi.org/10.52645/MJHS.2023.1.02
CZU: 616.711-002:616.721.7-001.7

Pag. 9-15

Borodin Serghei12
 
1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
2 Timofei Moșneaga Republican Clinical Hospital
 
Disponibil în IBN: 25 aprilie 2023


Rezumat

Introduction. Currently, the standard treatment of degenerative spondylolisthesis involves pedicle screw fixation to enhance the success of intervertebral fusion. The traditional pedicle screw techniques require extensive lateral muscle dissection, resulting in significantly increased surgical-related morbidity. To address some of these shortcomings, the Midline Lumbar Interbody Fusion (MIDLIF®) technique has recently been developed. It involves the combination of the cortical bone trajectory screw fixation of the spine with intervertebral cage placement to achieve a solid interbody fusion. So far, the clinical efficacy of the MIDLIF technique in the treatment of low-grade degenerative spondylolisthesis is still unknown. All existing publications are studies with a low level of relevance or scientific evidence. Materials and methods. A prospective randomized controlled trial was conducted between 2017 and 2022. The study analyzed the clinical and radiological effectiveness of the MIDLIF arthrodesis technique compared to the traditional lumbar interbody fusion techniques, used exclusively in the treatment of degenerative lumbar spondylolisthesis. Results. The study enrolled 112 eligible patients with degenerative low-grade spondylolisthesis, randomly assigned into two groups. At 1 year post-operatively, MIDLIF provided a significantly better improvement in postoperative relief of low back pain and radiating pain, as well as a significantly better functional recovery. Additionally, MIDLIF resulted in lower surgical morbidity compared to traditional fusion techniques. Conclusions. The success rate of MIDLIF arthrodesis is similar to that associated with traditional fusion techniques. At the same time, MIDLIF offers all the specific benefits of a minimally invasive approach, such as less postoperative pain, faster functional recovery, less bleeding, and fewer blood transfusions. Thus, MIDLIF might be a good alternative to the traditional intervertebral fusion techniques in the treatment of degenerative low-grade spondylolisthesis.

Cuvinte-cheie
MIDLIF, cortical bone trajectory, pedicle screws, degenerative spondylolisthesis