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SM ISO690:2012 FUIOR-BULHAC, Liliana, PETROVICI, Virgil, DEMENIUC, Iu., NEDBAILO, Ecaterina. Hemangiomul hepatic în diagnosticul prenatal: particularităţi ultrasonografice şi morfopatologice. In: Buletin de Perinatologie, 2012, nr. 3, pp. 82-88. ISSN 1810-5289. |
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Buletin de Perinatologie | |||||
Numărul 3 / 2012 / ISSN 1810-5289 | |||||
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Pag. 82-88 | |||||
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Background. Hepatic hemangioma is a benign vascular neoplasm, reported in 2-4% [5] of adult population with a
frequency range from necropsies within 1 to 7% cases [8, 11]. It is diagnosed incidentally in most pediatric cases. This
fact served as an argument to publish this case report of primary diagnosis in prenatal period.
Material and methods. In this article we present a pregnant 34 years woman with preterm delivery at 36 weeks of
gestation. The ultrasound investigation was performed at 34-35 weeks of gestation and was found the presence of massive
hepatic hemangioma in right lobe. The newborn died in the fi rst 5 hours of life. The postmortem morphopathological
examine elucidated macro - and microscopic features of the tumor.
Case report. The peculiarity of this case is the early diagnosis of intrauterine fetal hepatic cavernous hemangioma
within 34-35 weeks of gestation. We present the ultrasonographic aspects of hemangioma in the perinatal period. Are
very interesting the correlation data of ultrasound and histological features of hemangioma localized in the right hepatic
lobe, emphasizing structural aspects and differentiation of tumors, vascular systems and of umbilical vein vessels
in the fetus and new-born.
Macroscopic and microscopic features are refl ected in giant hepatic hemangioma that occupies 95% of the right hepatic
lobe. The peculiarities of placental circulation and the principles of diagnosis are elucidated. We give principles of
evolution and treatment and some advises in case of congenital infections associations in patients with this pathology. The
international studies results in diagnosis and treatment of patients with hepatic hemangioma are described in this work.
Conclusion. Giant liver hemangioma in the fetus and neonate is a malformative benign vascular-tumor with intrauterine
evolution of cardiovascular failure of diverse degree. The association of intrauterine or postnatal infection can
lead to intratumoral hemodynamic, relatively frequent thrombosis, calcinosis or diverse bleeding that will worsen the
postnatal newborn condition, with a possible death. |
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