Chia Salvia hispanica Lamiaceae family, also called Mexican chia or salba chia, is an annual herbaceous plant, native to Mexico and Guatemala, where it was an important crop for pre-Columbian Aztecs and other Mesoamerican Indian cultures, characterized by its high nutritional and therapeutically potential. Chia is mainly cultivated as a seed crop. The culinary uses of chia seed have been as a whole seed, seed flour, seed mucilage, and seed oil. Salvia hispanica seeds are one of the most-concentrated sources of alpha- linolenic acid (ALA), a plant-based omega-3 fatty acid. Recently interest has been raised on biomass production as a potential forage source opening alleys toward the integration of chia in crop-livestock systems, also as feedstock for renewable energy production. The objective of this research was to evaluate the quality of green mass from chia Salvia hispanica cultivated under the conditions of the Republic of Moldova, and the possibility to use them as fodder for animals and feedstock for biogas production, also the biomass quality of chia dry stalks after harvesting the seeds as feedstock for the production cellulosic ethanol. We found that the dry matter of the harvested whole plants contained 107 g/kg CP, 80 g/kg ash, 347 g/kg CF, 348 g/kg ADF, 517 g/kg NDF, 65 g/kg ADL, 283 g/kg Cel, 199 g/kg HC, 123 g/kg TSS, with nutritive value 61.79% DMD, RFV= 111, 12.19 MJ/kg DE, 10.1 MJ/kg ME, 6.03 MJ/kg NEl. The nitrogen content in the green mass substrate was 1.71% and estimated content of carbon– 51.1%, the C/N = 29.9 respectively, which played an important role in degradation and biomethane production. The biochemical methane potential of Salvia hispanica green mass substrate reached 298 l/kg ODM. The analysis of lignocellulose composition of chia dry stalks suggested that energy biomass contained 357 g/kg cellulose, 197 g/kg hemicellulose and 72 g/kg acid detergent lignin. The estimated theoretical ethanol yield from cell wall carbohydrates averaged 398 L/t. Chia Salvia hispanica can serve as multi-purpose crops for seed production, alternative forage and feedstock for renewable energy production.