Water pollution is one of the most pressing environmental problems in the world and requires drastic and urgent solutions. Pharmaceuticals are a special category of contaminants that are widely consumed in many aspects of life and are increasingly discovered in the environment, greatly affecting the quality of life. Currently, traditional water treatment systems do not offer adequate solutions for pharmaceutical drug elimination and there still isn`t a regulated criterion for their limitation in water. Obviously, it is imperative to develop and implement effective methods to eliminate this category of pollutants. Adsorption is one of the most effective and practical techniques for removing pollutants from water. The use of carbon adsorbents in treatment technologies is justified by the fact that activated carbon is able to remove a very wide spectrum of pollutants, almost entirely. In this paper we studied the adsorption parameters of vitamin B6 (Pyridoxine, C8H11NO3, MM 169.18) on three samples of activated carbon (AC-C, obtained from apricot kernels; CAN-8, obtained from walnut shells; Granucol FA, commercial carbon adsorbent). The effects of initial Pyridoxine concentrations, contact time, structural parameters of coals on the adsorption process were experimentally investigated. The adsorption kinetic curves were determined for three values of concentration (0.25 mmol/l, 0.5 mmol/l and 1.0 mmol/l) in a time interval between 10-300 minutes at 250C. The obtained data indicate that the degree of vitamin B6 immobilization on investigated activated carbon samples grows with increasing contact time between the two phases and depends on the initial concentration of Pyridoxine. The percentage of vitamin B6 removal decreases with increasing initial concentration, although the actual amount of Pyridoxine adsorbed per unit mass of adsorbent increased. It was observed a rapid adsorption of vitamin B6 during the initial stage of the adsorption process, followed by a gradual process. The equilibrium of the adsorption process between vitamin B6 solution and carbon adsorbent surface was achieved in 300 minutes. The effect of initial vitamin B6 concentration on the adsorption capacity of the researched coals was studied in the range of 0.25-2.5 mmol/l. The adsorption isotherms of vitamin B6 on AC-C, CAN-8 and Granucol FA coals were determined after establishing the equilibrium of the adsorption process (contact-stirring time – 300 minutes) at a temperature of 250C. The highest value of maximum adsorption (am) of vitamin B6 has been registered for autochthonous activated carbon AC-C (1.59 mmol/g), followed by an intermediate value for the CAN-8 sample (0.96 mmol/g). The lowest immobilization capacity of vitamin B6 was determined in the case of commercially activated carbon Granucol FA (0.74 mmol/g). The obtained results are in accordance with the structural parameters of the researched coals, with an obvious advantage of the autochthonous activated carbon AC-C, which has double value of am compared to the commercial coal sample Granucol FA. The realized research shows that pharmaceuticals such as vitamin B6 can be effectively removed from aqueous solutions using autochthonous activated carbon AC-C and CAN-8 as economic adsorbents.