It is established that the first place after the general incidence of the population in the North Development Region (NDR) is district Sangerei, being about 49 percent higher than the average on the NDR. On the second place is Bălți municipality, exceeding by 45.2% the average value registered in the NDR. On the third place in the general incidence of the population from the NDR, is placed district Glodeni, being 30.8% higher than RDN. The dynamics of respiratory diseases is in an increasing trend from 896.5 cases in 2010 to 1535.5 in 2019, and there is an increase of about 71.3 percentage points. Respiratory diseases are in the first place and constitute 44.7% of the total number of diseases. The largest number of these diseases in the NDR are in Bălți municipality, later Glodeni, Săngerei, etc. Diseases of the cardiovascular system remain in second place, with an average value of 194.0 / 10000 cases and constitute 7.3 percent of the total number. This group of diseases has an increasing character, from 173.0 / 10000 in the year 2010, to (239.0 / 10000 cases towards the year 2017. The highest value of the incidence in the NDR for Săngerei districts, Bălți municipality, Glodeni district and al. it is explained by the quality of the environmental components in the given localities. Among the Development Regions of the Republic of Moldova, the highest value, incidence, was registered in Centr DR (2780.6 / 10000), followed by UTA Gagauzia DR (2743.4 / 10000), NDR (2672.0 / 10000) and South DR with 2174.3 / 10000, cases. It is established that the general incidence of the population depends on the degree of environmental pollution (air emissions) in the given locality.