The effect of cytokinin-type compound on the capacity of the enzymatic and non-enzymatic system of antioxidant protection by plants in conditions of humidity fluctuation and repeated drought were studied. As subjects served the plants Glycine max (Merr) L.cultivar Nadejda, grown in the Mitcherlih vegetation pots with volume of 40 kg soil and exposed to the drought stress at the phases "first trifoliate leaf" and "flowering – pods formation”. The antioxidant protection capacity of soybeans pre-treated with cytokinin, thiourea and with the composition Polyel + phytohormones (AIA, Gb, CK)is ensured both by the intensification of the activity of antioxidant enzymes and by the increase of content of non-enzymatic substances with low molecular weight.After restoring the optimal moisture content, the plants pretreated with thiourea and Polyel + F more fully restore their functional processes.