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SM ISO690:2012 GÎLEA, Angela, LACUSTA, Victor, CEREŞ, Victoria, ŞINCARENCO, Irina. Acupunctura auriculară și indicii neurochimici ai activității convulsive. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 355. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | |||||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | |||||||||
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Pag. 355-355 | |||||||||
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Background. Auricular acupuncture (AA) is applied in the complex treatment of convulsive syndrome. Currently there are multiple hypotheses that propose the involvement of neurochemical cerebral mechanisms in the anti-convulsive actions of AA. Objective of the study. The study of AA’s influence on monoamine concentrations in different cerebral structures in animals with experimental convulsive activity. Material and Methods. The study was conducted on white rats from the Wistar line (n=100) where the syndrome of tabagic abstinence was modelled, and the cerebral convulsive activity was monitored through EEG. Monoamines were determined via the CLIR method in the hypothalamus, midbrain and the spinal bulb. The ear acupuncture points with a decreased skin electrical resistance were stimulated. Results. After performing AA a noradrenaline (NA) drop (compared to initial indexes), was registered in the: hypothalamus by 32% (p<0,01); midbrain by 49% (p<0,001) and the spinal bulb by 27% (p<0,001). Dopamine (DA) levels had risen in the hypothalamus by 49% (p<0,001) and in the spinal bulb by 55% (p<0,001). Serotonin (5-HT) had no significant changes in the studied cerebral structures (p>0,05). After AA stimulation, a tendency to normalize the EEG picture was registered, with a significant reduction of the paroxysmal index (p<0,05). Conclusion. In the experimental animals, AA had reduced convulsive activity in parallel with the differentiated activity of the neurochemical indexes: NA – dimished, DA – increased, 5-HT – no significant changes. |
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Cuvinte-cheie Auricular acupuncture, paroxysmal activity, monoamines, acupunctureă auriculară, activitate paroxismală, monoamine |
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