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SM ISO690:2012 MUNTEANU, Oxana, RUSU, Doina, TAMBALA, Diana, BOTNARU, Victor. Bronșiectaziile la pacienții adulți cu infecție hiv/sida: serie de cazuri. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 296. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Pag. 296-296 | ||||||
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Background. Immunodeficiencies should be suspected in cases of primary identified bronchiectasis in adults. Moldova is among countries with a continuous increase in the number of HIV-infected adults. Impaired immune system and chronic inflammation contribute to the progression of bronchiectasis in HIV patients. Objective of the study. To present the clinical, imaging, bacteriological peculiarities and outcomes in adult patients with bronchiectasis and HIV/AIDS infection. Material and Methods. This case series involved 11 patients with HIV/AIDS and bronchiectasis, selected from a prospective study on 490 patients diagnosed with non-cystic fibrosis bronchiectasis in a tertiary care hospital, between 2015–2019. Clinical, microbiological and radiological data, alongside, comorbidities and severity scores were analysed. Statistical analysis was performed using the SPSS 23 program. Results. The mean age was 39 years (range 25-65 years), with a male predominance (54%). A CD4 count <200 cells/mm3 was identified in 6 cases. The mReiff score (6.8±4.6) showed a significant correlation with Bhalla score (9.72±4.5), r=0.66 (p<0.05). BSI score (11.7±3) reflects better the severity of the disease, showing a significant correlation with the Bhalla imaging score (r=0.62, p<0.05). Assessing the impact of comorbidities (BACI index 5.4±4.3 and Charlson index 6.9±1.3), the BACI index better reflected the severity of the disease in this group of patients, demonstrating a strong correlation with BSI (r =0.62, p<0.05). Only 3 patients (27%) were alive after one year of follow-up. Conclusion. Bronchiectasis is one of the common pulmonary manifestations of HIV/AIDS infection, being responsible for a number of chronic respiratory symptoms and the risk of premature death. |
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Cuvinte-cheie bronchiectasis, HIV/AIDS, mReiff score, Bhalla score, BACI index, Bronşiectazii, HIV/SIDA, scorul mReiff, scorul Bhalla, indicele BACI |
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