Articolul precedent |
Articolul urmator |
390 10 |
Ultima descărcare din IBN: 2024-02-14 16:50 |
SM ISO690:2012 CHIŞLARI, Lia, RUSSU, Eugen, GROPPA, Liliana, CAZAC, Victor, ROTARU, Larisa. Disbioza intestinală în spondilita anchilozantă. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 203. |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | |||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | |||||
|
|||||
Pag. 203-203 | |||||
|
|||||
Descarcă PDF | |||||
Rezumat | |||||
Background. Ankylosing spondylitis (AS) is an inherited, autoimmune arthropathy that occurs in people exposed to an unknown but probably ubiquitous environmental trigger. There is a close relationship between bowel and spondyloarthritis, arthropathy follows either a gastrointestinal or urogenital infection. Objective of the study. The aim of this study was to determine whether the intestine in patients with AS has a distinct microbial signature compared to that in the intestine of healthy control subjects. Material and Methods. Intestinal microbial profiles were investigated in 37 patients with ankylosing spondylitis confirmed by the algorithm recommended by the National Clinical Protocol. Results. Our results showed that the intestinal microbial communities in patients with AS differ significantly (P <0.001) from those in healthy control subjects, caused by an abundance of more than 4 families of bacteria Lachnospiraceae (P = 0.001), Ruminococcaceae (P = 0.012), Porphyromonadaceae (P = 0.001) and Bacteroidaceae (P = 0.001)) and a decrease in the abundance family of bacteria ( Prevotellaceae (P = 0.004)). Conclusion. The microbial composition has been shown to correlate with disease activity. These results are consistent with the hypothesis that the genes associated with AS act, at least in part, by effects on the intestinal microbiome. |
|||||
Cuvinte-cheie ankylosing spondylitis, intestinal dysbiosis, spondilită anchilozantă, disbioză intestinală |
|||||
|