Age related non-Hodgkin lymphomas with primary abdominal lymph nodes involvement
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FEGHIU, Veronica. Age related non-Hodgkin lymphomas with primary abdominal lymph nodes involvement. In: MedEspera: International Medical Congress for Students and Young Doctors, Ed. 7th edition, 3-5 mai 2018, Chişinău. Chisinau, Republic of Moldova: 2018, 7, pp. 72-73.
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MedEspera
7, 2018
Congresul "International Medical Congress for Students and Young Doctors"
7th edition, Chişinău, Moldova, 3-5 mai 2018

Age related non-Hodgkin lymphomas with primary abdominal lymph nodes involvement


Pag. 72-73

Feghiu Veronica
 
”Nicolae Testemițanu” State University of Medicine and Pharmacy
 
Disponibil în IBN: 3 noiembrie 2020


Rezumat

Introduction. Non Hodgkin's Lymphomas ( are a heterogeneous group of malignant tumors of the lymphatic tissue that can develop from B or T, rarely from NK, cells. NHL may develop in any tissue or organ containing lymphatic tissue. One of the primary localizations o f NHL are the abdominal lymph nodes, with a primary involvement rate of 7.6 to 8.2%. Due to the topographic and anatomical features of this localization, in most cases the generalized stages of the disease are diagnosed, which negatively influences the out come of treatment and prognosis. Therefore, studying the clinical aspects of NHL with primary abdominal lymph nodes involvement is topical.Aim of the study. To assess the clinical and morphological features of NHL with primary abdominal lymph nodes invol vement depending on age. Materials and methods. Clinical and morphological features were studied in 67 patients with NHL with primary abdominal lymph nodes involvement, who were hospitalized at the Haematologic Clinic of the Oncological Institute from Rep ublic of Moldova. The age of the patients included in the study ranged from 2 to 73 years old as follows: children 0 18 years old 15 cases, adults: 19 39 years old 2 cases, 40 59 years old 34 cases and over 60 years old 16 cases. In all cases, the di agnosis was morphologically confirmed. Determining the degree of the tumoral process spreading was performed according to the International Classification, developed at Ann Arbor ( 1971. We performed a retrospective descriptive study. Results. Studying the NHL with primary abdominal lymph nodes involvement showed that the onset of NHL in abdominal nodes occurred more frequently in the age group of 40 59 years old ( followed by the patients over 60 years old ( children ( and rarely, patients form the age group 19 39 years old ( In all age groups men predominated ( The morphological examination determined that aggressive variants ( were more common than the indolent ones ( Stage I was found in 3 patients ( Stage II in 10 patients ( stage III in 14 patients(20.9%) and stage IV in 40 patients ( Most extranodal metastasis areas were spleen ( liver ( and bone marrow ( Less often extranodal areas were: nasopharynx ( pulmonary tissue ( pleura ( and rarely other tissues or organs. Conclusions. NHL with primary abdominal lymph nodes involvement developed more frequently in people that were 40 59 years old, predominantly in males. Aggressive variants of NHL predominated. The most frequent extranodal metastasis areas were spleen, liver and bone marrow.

Cuvinte-cheie
NHL, abdominal lymph nodes, age