Evaluation of the endothelial cell regenerative proprieties of the cornea in the culture media. results and prospects
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COCIUG, Adrian, MACAGONOVA, Olga, CUŞNIR, Valeriu, CUŞNIR, Vitalie, NACU, Viorel. Evaluation of the endothelial cell regenerative proprieties of the cornea in the culture media. results and prospects. In: IFMBE Proceedings: . 4th International Conference on Nanotechnologies and Biomedical Engineering, Ed. 4, 18-21 septembrie 2019, Chişinău. Switzerland: Springer Nature Switzerland AG, 2020, Ediția 4, Vol.77, pp. 601-605. ISBN 978-303031865-9. ISSN 16800737. DOI: https://doi.org/10.1007/978-3-030-31866-6_107
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IFMBE Proceedings
Ediția 4, Vol.77, 2020
Conferința "Conference on Nanotechnologies and Biomedical Engineering"
4, Chişinău, Moldova, 18-21 septembrie 2019

Evaluation of the endothelial cell regenerative proprieties of the cornea in the culture media. results and prospects

DOI:https://doi.org/10.1007/978-3-030-31866-6_107

Pag. 601-605

Cociug Adrian12, Macagonova Olga2, Cuşnir Valeriu2, Cuşnir Vitalie2, Nacu Viorel21
 
1 Human Tissue Bank, Moldova,
2 ”Nicolae Testemițanu” State University of Medicine and Pharmacy
 
 
Disponibil în IBN: 24 octombrie 2020


Rezumat

Preservation of the endothelial viability of the cornea is one of the main problems of the non-proliferative corneal transplantation, which creates a well-maintained status with the peripheral cell density decreasing throughout the life, about 30% higher than in the center of the cornea. The disruption of connections between cells adherent junctions correlates with a rapid decline of the proliferation of endothelial monostratified cells during the in vitro culture. The nutritional environment supplemented with EDTA proves that it has the ability to break the adherent junctions of the intercellular endothelial cells. The most widely used method of preservation is the cultured Tissue, “C”. It provides for the endothelial cells viability for 45 day.

Cuvinte-cheie
Descemet membrane, Endothelial cells, Keratoplasty, Limbal stem, Schwalbe’s line, Tissue “C”