We present a clinical case (a 44-years-old man) of bronchioloalveolar carcinoma with massive pulmonary embolism and nonatherosclerotic ischemia. The patient has been examined by noninvasive methods. The presence of myocardial infarction without ST-elevation (non STEMI) was established by electrocardiography and elevated activity of CK-MB isoenzyme. The nonatherosclerotic etiology of non STEMI was confirmed by the presence of metastasis of bronchioloalveolar carcinoma that compresses the coronary artery at morphopathological examination. Massive pulmonary embolism was another complication of bronchioloalveolar carcinoma and facilitated by the presence of deep venous thrombosis. Evolution of disease was poor and prognosis is unfavorable because of association of many risk factors that lead to patient's death.