Afiliat la F.C.E. ARENSIA Exploratory Medicine

2023 - 1

A randomized phase 1b trial of the active site polymerase inhibitor nucleotide ATI-2173 in patients with chronic hepatitis B virus infection

Squires Katherine E. , Ogilvie Lauren , Jucov Alina , Anastasiy Igor , Ghicavîi Nelea , Huguet Jade , Melara Rebeca , Constantineau Martin , De La Rosa Abel , Mayers Douglas

Journal of Viral Hepatitis

Nr. 1(30) / 2023 / ISSN 1352-0504 / ISSNe 1365-2893

Disponibil online 31 January, 2023

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2022 - 3

Editorial: protecting hypoxia-inducible factor 1a and gut integrity with GB004-a promising therapeutic approach for ulcerative colitis? Authors' reply

Danese Silvio , Levesque Barrett G. , Feagan Brian Gordon , Jucov Alina , Bhandari Bal Raj , Pai Rish K. , Taylor Meadows Kristen , Kirby Brian J. , Bruey Jean Marie , Olson Allan David , Osterhout Robin E. , van Biene Courtney , Ford Julia , Aranda Richard , Raghupathi Kartik , Sandborn William J.

Alimentary Pharmacology and Therapeutics

Nr. 6(55) / 2022 / ISSN 0269-2813 / ISSNe 1365-2036

Disponibil online 17 March, 2022

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Randomised clinical trial: a phase 1b study of GB004, an oral HIF-1α stabiliser, for treatment of ulcerative colitis

Danese Silvio , Levesque Barrett G. , Feagan Brian Gordon , Jucov Alina , Bhandari Bal Raj , Pai Rish K. , Taylor Meadows Kristen , Kirby Brian J. , Bruey Jean Marie , Olson Allan David , Osterhout Robin E. , van Biene Courtney , Ford Julia , Aranda Richard , Raghupathi Kartik , Sandborn William J.

Alimentary Pharmacology and Therapeutics

Nr. 4(55) / 2022 / ISSN 0269-2813 / ISSNe 1365-2036

Disponibil online 2 March, 2022

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HBsAg isoform dynamics during NAP-based therapy of HBeAg-negative chronic HBV and HBV/HDV infection

Bazinet Michel , Anderson Mark , Pântea Victor , Plăcintă Gheorghe , Moscalu Iurie , Cebotarescu Valentin , Cojuhari Lilia , Jimbei Paulina , Iarovoi Liviu , Smeşnoi Valentina , Musteaţă Tatiana , Jucov Alina , Dittmer Ulf , Gersch Jeffrey , Holzmayer Vera , Kuhns Mary C. , Cloherty Gavin A. , Vaillant Andrew

Hepatology Communications

Vol. 6, / 2022 / ISSN 2471-254X

Disponibil online 11 September, 2023

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2021 - 2

Analysis of HBsAg Immunocomplexes and cccDNA Activity During and Persisting After NAP-Based Therapy

Bazinet Michel , Anderson Mark , Pântea Victor , Plăcintă Gheorghe , Moscalu Iurie , Cebotarescu Valentin , Cojuhari Lilia , Jimbei Paulina , Iarovoi Liviu , Smeşnoi Valentina , Musteaţă Tatiana , Jucov Alina , Dittmer Ulf , Gersch Jeffrey , Holzmayer Vera , Kuhns Mary C. , Cloherty Gavin A. , Vaillant Andrew

Hepatology Communications

Vol. 5, / 2021 / ISSN 2471-254X

Disponibil online 12 September, 2023

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Benefit of transaminase elevations in establishing functional cure of HBV infection during nap-based combination therapy

Bazinet Michel , Pântea Victor , Plăcintă Gheorghe , Moscalu Iurie , Cebotarescu Valentin , Cojuhari Lilia , Jimbei Paulina , Iarovoi Liviu , Smeşnoi Valentina , Musteaţă Tatiana , Jucov Alina , Dittmer Ulf , Krawczyk Adalbert , Vaillant Andrew

Journal of Viral Hepatitis

Nr. 5(28) / 2021 / ISSN 1352-0504 / ISSNe 1365-2893

Disponibil online 11 May, 2021

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2020 - 4

Safety and Efficacy of 48 Weeks REP 2139 or REP 2165, Tenofovir Disoproxil, and Pegylated Interferon Alfa-2a in Patients With Chronic HBV Infection Naïve to Nucleos(t)ide Therapy

Bazinet Michel , Pântea Victor , Plăcintă Gheorghe , Moscalu Iurie , Cebotarescu Valentin , Cojuhari Lilia , Jimbei Paulina , Iarovoi Liviu , Smeşnoi Valentina , Musteaţă Tatiana , Jucov Alina , Dittmer Ulf , Krawczyk Adalbert , Vaillant Andrew

Gastroenterology

Nr. 8(158) / 2020 / ISSN 0016-5085 / ISSNe 1528-0012

Disponibil online 1 October, 2020

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Analysis of HBsAg levels, HBsAg isoforms, HBsAg immune complexes, HBV pregenomic RNA and HBcrAg dynamics during and after NAP-based combination therapy in the REP 301-LTF and REP 401 studies

Bazinet Michel , Anderson Mark , Pântea Victor , Plăcintă Gheorghe , Moscalu Iurie , Cebotarescu Valentin , Cojuhari Lilia , Jimbei Paulina , Iarovoi Liviu , Smeşnoi Valentina , Musteaţă Tatiana , Jucov Alina , Gersch Jeffrey , Holzmayer Vera , Kuhns Mary C. , Cloherty Gavin A. , Vaillant Andrew

Journal of Hepatology

Vol. 73, Supl. nr. 1 / 2020 / ISSN 0168-8278 / ISSNe 1600-0641

Disponibil online 11 April, 2024

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Safety, pharmacokinetic, biomarker, histologic, and rectal bleeding activity following treatment with the GUT-targeted, PHD-inhibitor and HIF-1α stabilizer GB004 in a phase 1b trial in MILD-to-moderate ulcerative colitis

Sandborn William J. , Feagan Brian Gordon , Danese Silvio , Jucov Alina , Bhandari Bal Raj , Raghupathi Kartik , Olson Allan David , van Biene Courtney , Opiteck G. , Ford Julia , Aranda Richard , Levesque Barrett G.

United European Gastroenterology Journal

Nr. 8(8) / 2020 / ISSN 2050-6406 / ISSNe 2050-6414

Disponibil online 11 April, 2024

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A combination of AT-527, a pan-genotypic guanosine nucleotide prodrug, and daclatasvir was well-tolerated and effective in HCV-infected subjects

Mungur Ounisha , Berliba Elina , Bourgeois Stefan , Cardona Marine , Jucov Alina , Good Steven Spencer , Moussa Adel , Pietropaolo Keith , Zhou Xiaojian , Brown Nathaniel , Sommadossi Jean Pierre

Journal of Hepatology

Vol. 73, Supl. nr. 1 / 2020 / ISSN 0168-8278 / ISSNe 1600-0641

Disponibil online 11 April, 2024

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