DFT evidence of mutual antioxidant action of caffeic acid and glutathione in their reactions with ABTS+•
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544.431.133:547.587.52c (1)
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GORBACHEV, Mikhail, GORINCHOY, Natalia, BALAN, Iolanta. DFT evidence of mutual antioxidant action of caffeic acid and glutathione in their reactions with ABTS+•. In: Integrare prin cercetare și inovare.: Ştiinţe ale naturii și exacte, 9-10 noiembrie 2023, Chișinău. Chisinau, Republica Moldova: Centrul Editorial-Poligrafic al USM, 2023, SNE, pp. 529-534. ISBN 978-9975-62-690-3.
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Integrare prin cercetare și inovare.
SNE, 2023
Conferința "Integrare prin cercetare și inovare."
Chișinău, Moldova, 9-10 noiembrie 2023

DFT evidence of mutual antioxidant action of caffeic acid and glutathione in their reactions with ABTS+•

CZU: 544.431.133:547.587.52c

Pag. 529-534

Gorbachev Mikhail, Gorinchoy Natalia, Balan Iolanta
 
Institute of Chemistry, MSU
 
Proiecte:
 
Disponibil în IBN: 2 aprilie 2024


Rezumat

It was shown that unlike other food acids, the caffeic one exhibits a significant synergistic effect with glutathione in the ABTS+• assay. It was found that the main stages of mechanism of this synergistic interaction is determined by the presence of the 3-OH and 4-OH hydroxyl groups in the structure of caffeic acid and the greater stability of its anion which contains the deprotonated 4-OH hydroxyl group compared with the anion with its deprotonated carboxyl group.

Cuvinte-cheie
synergistic effect, caffeic acid and glutathione, ABTS • test, DFT study