Neurological manifestations in children with SARS-COV-2 infection
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616.8-053.2:616.98:578.834 (2)
Neurologie. Neuropatologie. Sistem nervos (977)
Boli transmisibile. Boli infecţionase şi contagioase, stări febrile (587)
Virologie (446)
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CAPESTRU, Elena, HADJIU, Svetlana, CALCII, Cornelia, ITRATUC, Irina, CONSTANTIN, Olesea, CALISTRU, Iulia, REVENCO, Ninel. Neurological manifestations in children with SARS-COV-2 infection. In: Registrul maladiilor reumatice la copii: experiența Republicii Moldova, 31 martie 2023, Chişinău. Chişinău: Taicom (Ridgeone Group), 2023, p. 77.
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Registrul maladiilor reumatice la copii: experiența Republicii Moldova 2023
Simpozionul "Registrul maladiilor reumatice la copii: experiența Republicii Moldova"
Chişinău, Moldova, 31 martie 2023

Neurological manifestations in children with SARS-COV-2 infection

CZU: 616.8-053.2:616.98:578.834

Pag. 77-77

Capestru Elena12, Hadjiu Svetlana21, Calcii Cornelia12, Itratuc Irina21, Constantin Olesea12, Calistru Iulia21, Revenco Ninel12
 
1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
2 Institute of Mother and Child
 
 
Disponibil în IBN: 8 februarie 2024


Rezumat

Introduction. To date, few studies have investigated the specific neurological manifestations of SARS-CoV-2 infection in children. The studies reported prevalences from 3.8% to 44% of neurologic involvement in children with SARS-CoV-2. The aim: to study the type of neurological manifestations in children with SARS-CoV-2 infection. Material and Methods. I analyzed prospectively the patients with neurological manifestations associated with SARS-CoV-2 infection, aged from one month to 5 years, at Institute for Mother and Child. I divided these manifestations according to their type: specific and non-specific. I have used neurological testing, laboratory tests, and imaging investigations: electroencephalography evaluation (EEG). Statistic processing: t-student test and the confidence index 95 C. Results. Of the 138 hospitalized children with confirmed SARS-CoV-2 – only 46 cases (33,3%; 95CI 37,3129,29) were reported with neurological manifestations. Of these, 26 children (56.5%; 95CI63.81-49.19) had specific neurological manifestations, including toxic-infectious encephalopathy 21 (45.7%; 95CI 38.36-53.04) cases, seizures – 3 (6.5%; 95CI 2.86-10.14), myositis – 2 (4.3%; 95CI 1.29-7.31), and 20 (43.5%; 95CI 36.19-50.81) cases presented non-specific neurological manifestations: fatigue – 13 (28.3%; 95CI 21.66-34.94) cases, headaches – 5 (10.9%; 95CI 6.31-15.49) and anosmia/ageusia – 2 (4.3%; 95CI 1,29-7.31) cases. Conclusions. Although most studies have demonstrated the predominance of non-specific neurological manifestations, the results obtained in this study tell us that children with SARS-CoV-2 infection are at risk of developing specific neurological manifestations such as toxic-infectious encephalopathy and seizures.

Cuvinte-cheie
SARS-CoV-2 infection, neurological manifestations, children