The strongest external influences on our circadian rhythms under extreme working conditions are sunlight and ambient temperature, the timing of sleep, eating behavior, exercise, and social jetlag. Optimizing our daily habits to create a strong circadian rhythm can improve our sleep, alertness, metabolism, and overall health. Spatial and temporal differential theta rhytm-driven neuroplasticity is found in the hippocampus. A distinctive feature of the hippocampus is the presence of place cells in it, the ensemble of which forms a map of space when navigating in a certain environment. Experimental modeling was based on the forcible induction of physical overactivity during the rest period (the "night shift work" model) and during the active period (dark hours). Polysomnographic 24-hour recording was carried out in mature male rat (n=20) by using of electroencephalogram (EEG), electrohippocampogram (EHiG), electrooculogram (EOG) and 1 electromyogram (EMG) channels using “Spike4” software (Cambridge Electronic Design) and was accompanied by video behavior monitoring. Averaged total spectral power of hippocampus theta band in post-stimulus REM sleep episodes during postdeprivational recovery sleep was gradually increased by frequency and duration in comparison with baseline recordings. The theta-delta ratio was also elevated in EEG during restorative sleep. These findings suggest that physical overactivity could contributed to neuromodulation of synaptic plasticity in neocortexhippocampus networks, then lead to REM sleep rebound formation during recovery sleep. It is believed that EEG theta rhythm has entorhinal cortex-hippocampus originality. Theta rhythm (4-8 Hz) rebound may reflect intensification of explorative behavior and spatial memory formation. The hippocampal theta rhythm could be a therapeutic target due to its vital role in neuroplasticity, neuroprotection, learning, and memory.