The balance of power relations worldwide, ensured after Bretton Woods by the liberal order, can be considered ended. In its place, multipolarity can be glimpsed, which is currently not balanced. The important and rapid structural mutations that are taking place require specialists to analyze the material, human and territorial developments and implications. In addition to energy crises, raw materials crises, high inflation, and debt growth, we are currently witnessing the NorthSouth Split, a phenomenon that is actually both cause and effect. The headline is represented by the relations between the USA and China. We are witnessing an ever-increasing tension and distance between the US and China. Starting from the commercial tensions between the two great powers of the world, bilateral relations have reached a turning point. There is only one opponent in front of China: the USA, and it is pursuing a policy of discrediting alliances and delegitimizing US relations in the Asia-Pacific region. Another major change process we are currently witnessing is the attempt to isolate Russia through economic sanctions and political pressure. The formation of an Asian geo-political alliance, with the participation of Russia, China, Iran, India, Central Asia and the Caucasus, is the BRICS response. This alliance is based on the logic of regional commodity supply chains and the formation of new economic corridors.