Clary Sage (Salvia sclarea L.) is an eminent species of the Lamiaceae family that includes more than 1000 taxa. This species is widely used in medicine, pharmacology, phytotherapy and perfumery. Also, volatile oil and sclareol, two important commercial products, are produced industrially from inflorescences. Sclareol is the natural labdanic diterpenoid that is mainly used for the chemical synthesis of effective ambergris substitutes for the cosmetic and perfume industries. The demand for this product on the market is constantly increasing due to its wide range of uses in the production of flavoring and seasoning agents, preservatives, flavors for ennobling tobacco products or for toothpaste. The main world producers of sclareol are the companies Avoca, Frachem Technologies, Bontoux, Amyris, etc. The first producer has a share of about 55% of global production, and North America is the largest market, with a share of almost 70%. In the Republic of Moldova, the only producer of sclareol is the Moldavian-French company "MOLSALVIA SRL". Sclareol is extracted from the concrete obtained from the waste left after the distillation of the volatile oil of sage. Annually, the plant produces 63,600 kg of concrete, from which 2,700 kg of sclareol is obtained. After extracting the sclareol, 2 waste products result: No. 1 with a low content of sclareol (<5%) 22600 kg/year and No. 2 with a higher content of sclareol (~20%) 12700 kg/year. Unfortunately, currently none of these products are used. The aim of this study was to determine the chemical composition of waste No. 2 in order of its practical use. Initially, the waste was subjected to chromatographic fractionation on silica gel, by elution with equal volumes of solvents from apolar to polar and 8 fractions were obtaining. The GC-MS analysis of fractions 1-8 was performed on an Agilent 7890B system, equipped with a VF-WAXms 30m x 250μm x 0.25μm column in 30 minutes. Apart from sclareol (~28%), several dozens of constituents from different classes of compounds were identified. Of these can be mentioned: higher alkanes (decane, undecane, dodecane, nonacosane), oxygenated derivatives (cetylic alcohol, 2(E)-decenal, 2(Z)-decenal; myristic, capric and stearic acids; ethyl caprate, methyl linoleate, methyil oleate, ethyl oleate, ethyl linoleate), oxygenated monoterpenes (linalool, camfor, bornyl acetate), diterpenes (sclareol fitol) and triterpenes (scualene). On the basis of the obtained data, procedures for the enrichment of waste No. 2 for the repeated extraction of sclareol or its utilization in the perfumery or cosmetic industries can be developed.