The canids pollute the environment with parasitic forms, therefore they represent a major danger to human health and to the environment. The evaluation of the population of Vulpes vulpes (Linnaeus, 1758) in the Republic of Moldova according to the number of populated burrows in the spring period indicates an increased density of foxes of about 7-8 times. The purpose of this paper is revealing the role of foxes in the transmission of parasitic species in the zoonotic and epizootic chain in natural and anthropogenic ecosystems of the Republic of Moldova. Parasitological investigations were performed according to the methods of Popova, Baermann, Fuileborn, Darling and successive washing in the laboratory of Parasitology and Helminthology of the Institute of Zoology of SUM. In taxonomic aspect the parasite species identified in fox belong to 5 classes, 10 families, 11 genera and 12 species, while the infestation level was of 100%. The nosological characteristic of helminthoses includes 4 categories: Sporozoosis (isosporosis – 14.3%), Trematodosis (alariosis – 51.0%), Cestodosis (mezocestoidosis – 21.7%, teniosis – 27.0%), Nematodosis (syphaciosis – 20.0%, strongyloidiasis – 15.0%, toxocarosis – 59.0%, toxascariosis – 65,5%, anquilostomosis – 8.7%, trichurosis – 30.5%, capillariosis – 35.0%). The epidemiological features includes 3 categories of parasitic species. The category of parasitos is with zoonotic impact (parasitozoonosis) includes 10 species (A. alata, M. lineatus, Taeniaspp., S. obvelata, S. ratti, T. canis, T. leonina, A. caninum), with mixt impact (zoonotic+episootic) 3 species (H. taeniaformis larvae, M. lineatus larvae, C. hepatica), and in the category of invasions particular to rodents are 7 species (P. omphaloides, C. cricetorum, S. lobata, R. straminea, H. polygirus, M. muris, T. muris).