During the floristic survey (in 2022-2023) of the “Lower Prut Lakes” Ramsar site territory, in order to investigate the state of rare species of vascular plants, the herbarium samples from fifferent natural and seminatural habitats were collected. These samples were identified as Eclipta prostrata (L.) L. (Asteraceae family); Lathyrus cicera L. (Fabaceae); Polypogon monspeliensis (L.) Desf., Cenchrus longispinus (Hack.) Fernald (Poaceae). The samples of the collected herbaria from the studied area were critically processed in laboratory conditions using specific regional floras (the voucher specimens has been maintained in the Herbarium of the National Botanical Garden (Institute) of the Moldova State University). Eclipta prostrata (L.) L. is an annual or perennial herbaceous, with succulent, erect, ascending or prostrate stems, up to 60 (-100) cm tall, registered from 3 localities – the border between the Crihana Veche commune and the Manta commune, the Manolescu canal, in the commune of Slobozia Mare and the shore of Lake Beleu in the water (plot 7). Lathyrus cicera L. is an annual herbaceous, with glabrous, branched stems of 20-30 (-50) cm high, collected from a single locality in the vicinity of com. Slobozia Mare. It grows in small groups of several individuals in the lower part of the steep western slope as part of the phytocenosis of Ponto-Sarmatic steppes – *62C0 grasslands. Polypogon monspeliensis (L.) Desf. is an annual, tufted, with culms erect or geniculate, up to 60 cm tall, collected from a a single locality in the vicinity of com. Crihana Veche. On the Ramsar site it grows in the floodplain of the Prut river on the wet shore of a water basin near the Manta lake in the composition of grassy floodplain meadow. Cenchrus longispinus (Hack.) Fernald is an annual, tufted, sometimes decumbent, often with many branches arising from the base, up to 30 cm tall, collected in the vicinity of com. Brânza. Grows solitary or in small groups along the railway.