The Use Of Volatile Oils In The Magistralcompounding
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615.322.014.2:547.913:582 (2)
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GURANDA, Diana, CIOBANU, Cristina, CIOBANU, Nicolae, SOLONARI, Rodica, GURANDA, Victoria, FLOCEA, Vasile. The Use Of Volatile Oils In The Magistralcompounding. In: Direcții de reformare a sistemului farmaceutic din perspectiva cursului european al Republicii Moldova, Ed. Ediția a 2-a, 28 aprilie 2023, Chişinău. Comrat: Universitatea de Stat din Comrat, 2023, Ediția a 2-a, pp. 173-175. ISBN 978-5-88554-205-0.
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Direcții de reformare a sistemului farmaceutic din perspectiva cursului european al Republicii Moldova
Ediția a 2-a, 2023
Conferința "Direcții de reformare a sistemului farmaceutic din perspectiva cursului european al Republicii Moldova"
Ediția a 2-a, Chişinău, Moldova, 28 aprilie 2023

The Use Of Volatile Oils In The Magistralcompounding

CZU: 615.322.014.2:547.913:582

Pag. 173-175

Guranda Diana, Ciobanu Cristina, Ciobanu Nicolae, Solonari Rodica, Guranda Victoria, Flocea Vasile
 
”Nicolae Testemițanu” State University of Medicine and Pharmacy
 
 
Disponibil în IBN: 17 mai 2023


Rezumat

Introduction. Currently, volatile oils extracted from medicinal plants can be considered as alternative therapeutic remedies in the treatment of some diseases, or can be used to increase the effectiveness of prescribed drugs. A rather varied range of volatile oils are frequently used as starting or intermediate products for the production of medicinal formulations, characterized as active pharmaceutical principles or as adjuvants in the compounding of magistral forms [2]. Aim of the study. The study of the specialized literature using the databases Medline, PubMed, Embase regarding the use of pharmaceutical formulations containing volatile oils, as well as the study of the master's prescriptions from the Vasile Procopisin University Pharmaceutical Center (UPhC). Material and methods. The prescriptions of the doctors from the Vasile Procopisin UPhC for the period September-December 2022 served as materials. Results. Currently, in classical medicine, complex preparations containing volatile oils from several medicinal plants are used that exhibit the following effects: bactericidal, anti-inflammatory and antiseptic, improve the qualitative composition of the microflora of the upper respiratory tract and increase local immunity. The significant prevalence of acute respiratory diseases, their negative impact on the state of human systems, the lack of effectiveness of prevention and rehabilitation methods determine the importance of the medical aspects of this problem, their social significance. Medical specialists prescribe pharmaceutical formulations containing volatile oils in the form of mixtures, aromatic waters, nasal ointments, etc. The medicinal properties of mint - Mentha piperita L. (Family Lamiaceae), perennial herbaceous plant, have been known since ancient times. The medicinal vegetal product is Menthae folia, as well as the volatile oil obtained from the leaves, which have pronounced antibacterial properties. Mint leaves contain active principles such as: monocyclic terpenes: menthol (45-70%), menthone (8-24%), other terpenic hydrocarbons: pinene, terpinene, limonene, camphene, which come with actions: antiseptic, antidiarrheal, general stimulants of digestive and anti-inflammatory function [1]. In the Vasile Procopisin UPhC according to medical prescriptions, mint water is prepared by the method of dissolving the volatile oil, according to the Romanian Pharmacopoeia. The volatile peppermint oil is dispersed with talc to which is added the purified water heated to 35-40ºC with preservatives, gradually, the mixture is vigorously shaken periodically for an hour, after which it is left to rest in the dark. After 24 hours it is filtered and made up to 1000 ml m/v. The obtained aromatic water is used to prepare the mixture with the composition: valerian tincture, potassium iodide, sodium bromide, magnesium sulfate, ascorbic acid, glucose and mint water, which is recommended for use in the treatment of mastopathy, hot flushes in menopause, as a sedative, tranquilizer and antidepressant. Another oil frequently used in masterful formulations is the volatile eucalyptus oil obtained from the eucalyptus shrub, Eucalyptus globulus L. (Family Myrtaceae), which contains piperitone (40-50%), terpenes (30%), flavonoids, tannins, etc. It is currently prescribed by doctors in the form of a nasal ointment used in respiratory diseases: sinusitis, allergic rhinitis, sinusitis and frontitis.

Cuvinte-cheie
volatile oil, medical prescriptions, treatment, drug formulations